Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 14/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | ELOC | Q15369 | 3/20 | 0.32 |
| ▸ | ELOB | Q15370 | 3/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL679793 | 0.78 | KDM4E (0.53) | VHLKDM4ESLC6A3 | |
| SCHEMBL26384247 | 0.77 | VHL (0.50) | VHLKDM4EELOCELOB | |
| SCHEMBL25006423 | 0.73 | VHL (0.47) | VHLKDM4EELOCELOB | |
| SCHEMBL8712652 | 0.72 | MAOB (0.48) | MAOB | |
| SCHEMBL16276343 | 0.72 | VHL (0.59) | VHLKDM4EELOCELOB | |
| SCHEMBL24440459 | 0.71 | VHL (0.51) | VHLKDM4EELOCELOB | |
| SCHEMBL1987774 | 0.70 | MAOB (0.46) | KDM4EMAOB | |
| SCHEMBL19661678 | 0.70 | VHL (0.53) | VHLKDM4EELOCELOB | |
| SCHEMBL23205423 | 0.70 | VHL (0.57) | VHLELOCELOB | |
| SCHEMBL18579787 | 0.70 | VHL (0.57) | VHLKDM4EELOCELOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109678852-B | 6-oxo-hexahydropyrimidine derivative, preparation method and pharmaceutical application thereof | 南京中医药大学 | 2022-04-19 | — | — | CN | disclosed |