Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | AGXT | P21549 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ARG2 | P78540 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8674538 | 0.95 | TAAR1 (0.48) | MAOBTAAR1ALDH1A1CA1TP53 | |
| SCHEMBL69726 | 0.85 | MAOB (0.57) | MAOBTAAR1ALDH1A1CA1TP53 | |
| SCHEMBL8709601 | 0.83 | GPR52 (0.49) | MAOBTAAR1ALDH1A1CA1TP53 | |
| SCHEMBL4304998 | 0.82 | NPC1 (0.44) | MAOBALDH1A1LMNAGAATSHR | |
| SCHEMBL8710305 | 0.82 | TRPA1 (0.50) | MAOBALDH1A1TP53KMT2ALMNA | |
| SCHEMBL6435082 | 0.82 | NPC1 (0.44) | MAOBALDH1A1LMNAGAATSHR | |
| SCHEMBL5197801 | 0.80 | MAPT (0.51) | ALDH1A1CA1TP53MAPK1KMT2A | |
| SCHEMBL654153 | 0.80 | NFE2L2 (0.52) | MAOBALDH1A1KMT2ATSHRMAPT | |
| SCHEMBL8199494 | 0.80 | MAOB (0.46) | MAOBALDH1A1CA1MAPK1KMT2A | |
| SCHEMBL2528043 | 0.80 | TAAR1 (0.50) | MAOBTAAR1ALDH1A1CA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998000153-A1 | AMIDES | ELI LILLY AND COMPANY (US) | 1998-01-08 | — | — | WO | disclosed |