Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | BCHE | P06276 | 3/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.47 |
| ▸ | CHKA | P35790 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.45 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28645295 | 0.87 | ALDH1A1 (0.65) | ALDH1A1HTTBCHEACHEKDM4E | |
| SCHEMBL6225770 | 0.86 | ALDH1A1 (0.63) | ALDH1A1HTTBCHEACHEKDM4E | |
| SCHEMBL20210279 | 0.81 | KDM4E (0.63) | ALDH1A1HTTBCHEACHEKDM4E | |
| SCHEMBL6704155 | 0.79 | ALDH1A1 (0.51) | ALDH1A1HTTKDM4ESMN1; SMN2HRH3 | |
| SCHEMBL28192273 | 0.78 | ALDH1A1 (0.96) | ALDH1A1HTTKDM4ESMN1; SMN2HRH3 | |
| SCHEMBL28636678 | 0.78 | ALDH1A1 (0.65) | ALDH1A1HTTBCHEACHEKDM4E | |
| SCHEMBL13293320 | 0.76 | ALDH1A1 (1.00) | ALDH1A1HTTKDM4ESMN1; SMN2HRH3 | |
| SCHEMBL26351812 | 0.76 | ALDH1A1 (0.62) | ALDH1A1HTTKDM4ESMN1; SMN2HRH3 | |
| SCHEMBL26351817 | 0.76 | ALDH1A1 (0.62) | ALDH1A1HTTKDM4ESMN1; SMN2HRH3 | |
| SCHEMBL2879886 | 0.76 | HRH3 (0.68) | ALDH1A1KDM4ESMN1; SMN2HRH3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216758-A1 | Pyridone Compounds | MSD K.K. (JP) | 2010-08-26 | — | — | US | disclosed |
| EP-1916239-A1 | PYRIDONE COMPOUND | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-04-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216758-A1 | Pyridone Compounds | NPY1R, MC5R, MC1R | ALDH1A1 1631/4885HTT 3957/4885BCHE 2805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.