Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | ESRRG | P62508 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27703471 | 0.81 | KCNH2 (0.49) | SLC18A3SIGMAR1ALDH1A1 | |
| SCHEMBL27765287 | 0.80 | SLC18A3 (0.53) | SLC18A3SLC6A2SLC6A3PGRDPP4 | |
| SCHEMBL1475593 | 0.76 | SLC18A3 (0.55) | SLC18A3ESRRGDPP4FAAHTRPV6 | |
| SCHEMBL1284446 | 0.74 | SLC18A3 (0.52) | SLC18A3ESRRGTRPV6SIGMAR1ALDH1A1 | |
| SCHEMBL853823 | 0.74 | SLC18A3 (0.58) | SLC18A3ESRRGDPP4FAAHTRPV6 | |
| SCHEMBL17630267 | 0.73 | SLC18A3 (0.51) | SLC18A3ESRRGDPP4FAAHTRPV6 | |
| SCHEMBL21526510 | 0.73 | SLC18A3 (0.54) | SLC18A3ESRRGDPP4FAAHGAA | |
| SCHEMBL4184580 | 0.72 | ALDH1A1 (0.58) | SLC18A3DPP4FAAHGAAALDH1A1 | |
| SCHEMBL27765289 | 0.72 | SLC18A3 (0.50) | SLC18A3PGRESRRGDPP4FAAH | |
| SCHEMBL1476579 | 0.72 | SLC18A3 (0.53) | SLC18A3ESRRGDPP4FAAHGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101048418-A | PI 3-kinase | BOEHRINGER INGELHEIM INT (DE) | 2007-10-03 | — | — | CN | disclosed |