SCHEMBL28768435

SCHEMBL28768435

c1ccc2c(c1)-c1nc-2nc2[nH]c(nc3nc(nc4[nH]c(n1)c1ccccc41)-c1ccccc1-3)c1c(Oc3cccc4ccccc34)cccc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 2/20 0.39
▸ ALDH1A1 P00352 2/20 0.39
▸ GAA P10253 2/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ NPSR1 Q6W5P4 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ KDM1A O60341 1/20 0.36
▸ RCOR1 Q9UKL0 1/20 0.36
▸ SIRT2 Q8IXJ6 1/20 0.34
▸ SIRT1 Q96EB6 1/20 0.34
▸ SIRT3 Q9NTG7 1/20 0.34
▸ RECQL P46063 2/20 0.33
▸ ESRRA P11474 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ HTT P42858 1/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ THRB P10828 1/20 0.33
▸ APEX1 P27695 1/20 0.33
▸ BLM P54132 1/20 0.33
▸ KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5972535 0.94 MEN1 (0.36) MAPTALDH1A1GAAKDM4ENPSR1
SCHEMBL7131959 0.86 BRD4 (0.36) MAPTALDH1A1KDM4ENPSR1RECQL
SCHEMBL8418862 0.85 LMNA (0.36) MAPTALDH1A1KDM4ENPSR1RECQL
SCHEMBL8625005 0.83 CYP1A2 (0.44) MAPTALDH1A1KDM4ENPSR1LMNA
SCHEMBL1393560 0.83 MEN1 (0.35) MAPTALDH1A1KDM4ENPSR1RECQL
SCHEMBL8936396 0.83 MEN1 (0.35) MAPTALDH1A1KDM4ENPSR1RECQL
SCHEMBL5709277 0.83 MEN1 (0.35) MAPTALDH1A1KDM4ENPSR1RECQL
SCHEMBL7520606 0.83 HTT (0.41) MAPTALDH1A1KDM4EL3MBTL1RECQL
SCHEMBL28550848 0.82 MEN1 (0.36) MAPTALDH1A1GAAKDM4ENPSR1
SCHEMBL13727682 0.82 KDM4E (0.44) MAPTALDH1A1GAAKDM4ERECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102610627-B Stacked organic photosensitive devices UNIV PRINCETON 2014-12-24 — — CN disclosed
CN-102610627-A Stacked organic photosensitive devices UNIV PRINCETON 2012-07-25 — — CN disclosed
CN-101651183-B Stacked organic photosensitive devices UNIV PRINCETON 2012-06-27 — — CN disclosed
CN-101044640-B Stacked organic photosensitive devices UNIV PRINCETON 2010-06-02 — — CN disclosed
CN-101651183-A stacked organic photosensitive devices UNIV PRINCETON US 2010-02-17 — — CN disclosed
CN-100565959-C Stacked organic photosensitive devices UNIV PRINCETON (US) 2009-12-02 — — CN disclosed
CN-101088179-A Stacked organic photosensitive devices UNIV PRINCETON (US) 2007-12-12 — — CN disclosed
CN-101044640-A Stacked organic photosensitive devices UNIV PRINCETON (US) 2007-09-26 — — CN disclosed
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