Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | EGFR | P00533 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | RAD52 | P43351 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NSD2 | O96028 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12658885 | 0.91 | MAPT (0.55) | MAOAMAPTMEN1KMT2APOLB | |
| SCHEMBL1071678 | 0.91 | MEN1 (0.57) | MAOAMAPTMEN1KMT2APOLB | |
| SCHEMBL1993795 | 0.81 | MAOA (0.72) | MAOAMAPTMEN1KMT2APOLB | |
| SCHEMBL9819645 | 0.80 | MEN1 (0.55) | MAOAMAPTMEN1KMT2APOLB | |
| SCHEMBL2840051 | 0.80 | MAOA (0.52) | MAOAMAPTMEN1KMT2APOLB | |
| SCHEMBL30238611 | 0.80 | MAOA (0.52) | MAOAMAPTMEN1KMT2APOLB | |
| SCHEMBL31616824 | 0.80 | MAOA (0.49) | MAOAMAPTMEN1KMT2APOLB | |
| SCHEMBL8064424 | 0.80 | MAOA (0.49) | MAOAMAPTMEN1KMT2APOLB | |
| SCHEMBL11485130 | 0.79 | MAOA (0.61) | MAOAMAPTMEN1KMT2APOLB | |
| SCHEMBL2831572 | 0.78 | MAPT (0.54) | MAOAMAPTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101094879-B | Polysiloxane prepolymers for biomedical devices | BAUSCH & LOMB | 2011-08-10 | — | — | CN | disclosed |
| CN-101094878-B | Polysiloxane prepolymers for biomedical devices | BAUSCH & LOMB | 2011-04-13 | — | — | CN | disclosed |
| CN-101094879-A | Polysiloxane prepolymers for biomedical devices | BAUSCH & LOMB (US) | 2007-12-26 | — | — | CN | disclosed |
| CN-101094878-A | Polysiloxane prepolymers for biomedical devices | BAUSCH & LOMB (US) | 2007-12-26 | — | — | CN | disclosed |