Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | LPL | P06858 | 12/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 12/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12099849 | 0.87 | CA1 (0.51) | CA1CA2CA9LPLLIPG | |
| SCHEMBL1129399 | 0.84 | CA1 (0.49) | CA1CA2CA9LPLLIPG | |
| SCHEMBL16622963 | 0.84 | CA1 (0.49) | CA1CA2CA9LPLLIPG | |
| SCHEMBL23575375 | 0.82 | CA1 (0.48) | CA1CA2CA9LPLLIPG | |
| SCHEMBL1129134 | 0.82 | CA1 (0.48) | CA1CA2CA9LPLLIPG | |
| SCHEMBL586040 | 0.82 | HRH3 (0.51) | CA1CA2CA9LPLLIPG | |
| SCHEMBL14230903 | 0.81 | CA1 (0.47) | CA1CA2CA9LPLLIPG | |
| SCHEMBL17669442 | 0.81 | HRH3 (0.39) | CA1CA2CA9CYP2D6KCNH2 | |
| SCHEMBL15740980 | 0.81 | CA1 (0.43) | CA1CA2CA9LPLLIPG | |
| SCHEMBL14863631 | 0.80 | HRH1 (0.50) | CA1CA2CA9LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114394965-A | Triazolopyridine compound and preparation method and application thereof | 深圳市乐土生物医药有限公司 | 2022-04-26 | — | — | CN | disclosed |