Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Piperazine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperazine SCHEMBL5380983 | 0.94 | — | — | |
| Piperazine SCHEMBL5370035 | 0.94 | HIF1A (0.75) | — | |
| Piperazine SCHEMBL5370033 | 0.94 | — | — | |
| Piperazine SCHEMBL27901557 | 0.94 | — | — | |
| Bromide SCHEMBL6017046 | 0.88 | HIF1A (0.86) | — | |
| Piperazine SCHEMBL1224331 | 0.88 | — | — | |
| Piperazine SCHEMBL11442745 | 0.88 | — | — | |
| Piperazine SCHEMBL632421 | 0.88 | — | — | |
| Bromide SCHEMBL3966683 | 0.88 | HIF1A (0.86) | — | |
| Piperazine SCHEMBL1005658 | 0.88 | HIF1A (0.86) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100463720-C | Phase-transferring catalyst containing dinaphthalene chiral double-spiral quaternary ammonium and its production | UNIV TIANJIN (CN) | 2009-02-25 | — | — | CN | disclosed |
| CN-101073780-A | Phase-transferring catalyst containing dinaphthalene chiral double-spiral quaternary ammonium and its production | UNIV TIANJIN (CN) | 2007-11-21 | — | — | CN | disclosed |