Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | PPARA | Q07869 | 4/20 | 0.57 |
| ▸ | PPARG | P37231 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 4/20 | 0.49 |
| ▸ | CTSS | P25774 | 4/20 | 0.49 |
| ▸ | CTSK | P43235 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | CTSD | P07339 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4245909 | 0.93 | ATM (0.57) | ATMPPARAPPARGL3MBTL1CTSL | |
| SCHEMBL7616012 | 0.89 | ATM (0.60) | ATMPPARAPPARGL3MBTL1CTSL | |
| SCHEMBL2851734 | 0.87 | ATM (0.64) | ATMPPARAPPARGL3MBTL1CTSL | |
| SCHEMBL2851655 | 0.87 | ATM (0.57) | ATMPPARAPPARGL3MBTL1CTSL | |
| SCHEMBL2875084 | 0.85 | ATM (0.55) | ATMPPARAPPARGL3MBTL1CTSL | |
| SCHEMBL2853770 | 0.85 | ATM (0.55) | ATMPPARAPPARGL3MBTL1CTSL | |
| SCHEMBL2849807 | 0.85 | ATM (0.55) | ATMPPARAPPARGL3MBTL1CTSL | |
| SCHEMBL4249993 | 0.83 | ATM (0.55) | ATML3MBTL1CTSLCTSSCTSK | |
| SCHEMBL4244192 | 0.83 | ATM (0.60) | ATML3MBTL1CTSLCTSSCTSK | |
| SCHEMBL2861702 | 0.82 | ATM (0.50) | ATMPPARAPPARGL3MBTL1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651596-B1 | NOVEL DERIVATIVES OF 4,4'-DITHIOBIS-(3-AMINOBUTANE-1-SULFONATES) AND COMPOSITIONS COMPRISING THE SAME | INST NAT SANTE RECH MED (FR) | 2010-01-13 | — | — | EP | disclosed |
| EP-1651596-A1 | NOVEL DERIVATIVES OF 4,4'-DITHIOBIS-(3-AMINOBUTANE-1-SULFONATES) AND COMPOSITIONS COMPRISING THE SAME | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2006-05-03 | — | — | EP | disclosed |
| WO-2005014535-A1 | NOVEL DERIVATIVES OF 4,4'-DITHIOBIS-(3-AMINOBUTANE-1-SULFONATES) AND COMPOSITIONS COMPRISING THE SAME | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2005-02-17 | — | — | WO | disclosed |