Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.53 |
| ▸ | CTSK | P43235 | 3/20 | 0.50 |
| ▸ | CTSL | P07711 | 2/20 | 0.50 |
| ▸ | CTSS | P25774 | 2/20 | 0.50 |
| ▸ | CTSD | P07339 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2851655 | 0.94 | ATM (0.57) | ATMTRPM8CTSKCTSLCTSS | |
| SCHEMBL4245571 | 0.90 | ATM (0.53) | ATMTRPM8CTSKCTSLCTSS | |
| SCHEMBL4248093 | 0.90 | ATM (0.53) | ATMTRPM8CTSKCTSLCTSS | |
| SCHEMBL4245909 | 0.87 | ATM (0.57) | ATMTRPM8CTSKCTSLCTSS | |
| SCHEMBL4242934 | 0.85 | ATM (0.48) | ATMTRPM8CTSKCTSLCTSS | |
| SCHEMBL4244192 | 0.85 | ATM (0.60) | ATMTRPM8CTSKCTSLCTSS | |
| SCHEMBL4251702 | 0.85 | ATM (0.48) | ATMTRPM8CTSKCTSLCTSS | |
| SCHEMBL2849807 | 0.83 | ATM (0.55) | ATMCTSKCTSLCTSSCTSD | |
| SCHEMBL2853770 | 0.83 | ATM (0.55) | ATMCTSKCTSLCTSSCTSD | |
| SCHEMBL2875084 | 0.83 | ATM (0.55) | ATMCTSKCTSLCTSSCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582797-B2 | Derivatives of 4,4′-dithiobis-(3-aminobutane-1-sulfonates) and compositions comprising the same | INSTITUTE NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2009-09-01 | — | — | US | disclosed |
| US-20060205695-A1 | Novel derivatives of 4,4' dithiobis-(3-aminobutane-1-1-sulfonates) and compositions comprising the same | INSTITUT NATINAL DE LA SANTE ET DE LA RECHERECHE (INSERM) (FR) | 2006-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205695-A1 | Novel derivatives of 4,4' dithiobis-(3-aminobutane-1-1-sulfonates) and compositions comprising the same | AGTR1, AGTR2, AGT | ATM 1309/4885TRPM8 2698/4885CTSK 4816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.