Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4647849 | 0.82 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDPOLBHSD17B10 | |
| SCHEMBL3786488 | 0.80 | PIM2 (0.54) | ALDH1A1KDM4EHPGDPOLBHSD17B10 | |
| SCHEMBL3786486 | 0.80 | PIM2 (0.54) | ALDH1A1KDM4EHPGDPOLBHSD17B10 | |
| SCHEMBL29551688 | 0.80 | PIM2 (0.54) | ALDH1A1KDM4EHPGDPOLBHSD17B10 | |
| SCHEMBL23683819 | 0.80 | AOC3 (0.62) | ALDH1A1KDM4EHPGDPOLBHSD17B10 | |
| SCHEMBL30475671 | 0.80 | AOC3 (0.62) | ALDH1A1KDM4EHPGDPOLBHSD17B10 | |
| Hydrochloric Acid SCHEMBL20424596 | 0.79 | AOC3 (0.60) | ALDH1A1KDM4EHPGDPOLBHSD17B10 | |
| SCHEMBL24297830 | 0.77 | AOC3 (0.62) | ALDH1A1KDM4EHPGDPOLBHSD17B10 | |
| SCHEMBL857231 | 0.76 | CYP11B1 (0.57) | ALDH1A1KDM4EHPGDPOLBHSD17B10 | |
| SCHEMBL17221698 | 0.76 | CYP11B1 (0.57) | ALDH1A1KDM4EHPGDPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114891070-A | Anthelmintic depsipeptide compounds | 勃林格殷格翰动物保健美国公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-107835818-B | Anthelmintic depsipeptide compounds | 勃林格殷格翰动物保健美国公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-108699052-B | Anthelmintic depsipeptide compounds | 勃林格殷格翰动物保健美国公司 | 2022-04-29 | — | — | CN | disclosed |