Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1631121 | 0.81 | PSEN1 (0.38) | TRPV4SCN1ASCN5ASCN8AS1PR3 | |
| SCHEMBL28772202 | 0.78 | S1PR3 (0.36) | TRPV4SCN1ASCN5ASCN8AS1PR3 | |
| SCHEMBL1632894 | 0.72 | PSEN1 (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL1631914 | 0.71 | PSEN1 (0.39) | TRPV4SCN1ASCN5ASCN8AS1PR3 | |
| SCHEMBL12762203 | 0.68 | PSEN1 (0.38) | TRPV4SCN1ASCN5ASCN8AS1PR3 | |
| SCHEMBL1632260 | 0.67 | PSEN1 (0.53) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL1631232 | 0.66 | SCN1A (0.41) | SCN1ASCN5ASCN8AS1PR3TNF | |
| SCHEMBL1632245 | 0.66 | PSEN1 (0.37) | SCN1ASCN5ASCN8AS1PR3TNF | |
| SCHEMBL1633173 | 0.66 | PSEN1 (0.40) | SCN1ASCN5ASCN8ATNFPSEN1 | |
| SCHEMBL1631897 | 0.64 | PSEN1 (0.48) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100378072-C | Heterocyclic methyl sulfone derivative | DAIICHI SEIYAKU CO (JP) | 2008-04-02 | — | — | CN | disclosed |