Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 10/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 2/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ATR | Q13535 | 1/20 | 0.31 |
| ▸ | FLT1 | P17948 | 1/20 | 0.31 |
| ▸ | FLT4 | P35916 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1631121 | 0.82 | PSEN1 (0.38) | S1PR3S1PR1SCN1ASCN5ASCN8A | |
| SCHEMBL28772200 | 0.78 | TRPV4 (0.33) | S1PR3S1PR1S1PR4SCN1ASCN5A | |
| SCHEMBL1632894 | 0.73 | PSEN1 (0.42) | PIK3CAMTORATR | |
| SCHEMBL1631914 | 0.72 | PSEN1 (0.39) | S1PR3S1PR1S1PR4SCN1ASCN5A | |
| SCHEMBL12762203 | 0.70 | PSEN1 (0.38) | S1PR3S1PR1SCN1ASCN5ASCN8A | |
| SCHEMBL1632260 | 0.68 | PSEN1 (0.53) | — | |
| SCHEMBL1632245 | 0.67 | PSEN1 (0.37) | S1PR3S1PR1SCN1ASCN5ASCN8A | |
| SCHEMBL1631232 | 0.67 | SCN1A (0.41) | S1PR3SCN1ASCN5ASCN8ATNF | |
| SCHEMBL1632122 | 0.65 | PSEN1 (0.43) | SCN1ASCN5ASCN8APIK3CAMTOR | |
| SCHEMBL1631897 | 0.65 | PSEN1 (0.48) | PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100378072-C | Heterocyclic methyl sulfone derivative | DAIICHI SEIYAKU CO (JP) | 2008-04-02 | — | — | CN | disclosed |