Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287235 | 0.81 | TSHR (0.63) | NPSR1TP53TDP1HTTHSD17B10 | |
| SCHEMBL286986 | 0.81 | MAPT (0.46) | NPSR1TP53TDP1HTTHSD17B10 | |
| SCHEMBL287827 | 0.79 | ALDH1A1 (0.41) | TP53HTTKDM4EALDH1A1LMNA | |
| SCHEMBL659989 | 0.78 | MEN1 (0.44) | TP53TDP1HSD17B10KDM4EALDH1A1 | |
| SCHEMBL660292 | 0.75 | ALDH1A1 (0.43) | TP53HTTKDM4EALDH1A1LMNA | |
| SCHEMBL286819 | 0.73 | MAPT (0.43) | HTTKDM4EALDH1A1LMNARAB9A | |
| SCHEMBL9575455 | 0.71 | KDM4E (0.80) | NPSR1TP53TDP1HTTHSD17B10 | |
| SCHEMBL31730773 | 0.71 | KDM4E (0.80) | NPSR1TP53TDP1HTTHSD17B10 | |
| SCHEMBL14855798 | 0.70 | SMN1; SMN2 (0.75) | NPSR1TP53TDP1HTTHSD17B10 | |
| SCHEMBL23068994 | 0.70 | CA12 (0.63) | NPSR1TP53TDP1HTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427432-A2 | NOVEL HETEROCYCLIC COMPOUNDS | Torrent Pharmaceuticals Limited (IN) | 2012-03-14 | — | — | EP | claimed |
| WO-2010128528-A2 | NOVEL HETEROCYCLIC COMPOUNDS | TORRENT PHARMACEUTICALS LIMITED (IN) | 2010-11-11 | — | — | WO | claimed |