Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 6/20 | 0.42 |
| ▸ | CA1 | P00915 | 5/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2874733 | 0.91 | TSHR (0.43) | USP2TSHRCA2CA1FOLH1 | |
| SCHEMBL2876713 | 0.88 | USP2 (0.40) | USP2TSHRFOLH1MMP1MMP2 | |
| SCHEMBL19188339 | 0.83 | TSHR (0.54) | USP2TSHRCA2CA1HDAC7 | |
| SCHEMBL13575672 | 0.83 | TSHR (0.54) | USP2TSHRCA2CA1HDAC7 | |
| SCHEMBL28012223 | 0.83 | TSHR (0.54) | USP2TSHRCA2CA1HDAC7 | |
| SCHEMBL2867871 | 0.82 | TSHR (0.55) | USP2TSHRCA2CA1FOLH1 | |
| SCHEMBL13609174 | 0.82 | TSHR (0.71) | USP2TSHRCA2CA1MMP1 | |
| SCHEMBL2872456 | 0.81 | TSHR (0.44) | USP2TSHRCA2CA1FOLH1 | |
| SCHEMBL2871456 | 0.81 | CA2 (0.44) | USP2TSHRCA2CA1FOLH1 | |
| SCHEMBL2877948 | 0.80 | USP2 (0.57) | USP2TSHRCA2CA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1570835-B1 | Composition for the permanent deformation of the hair comprising at least one carboxydithiol | OREAL (FR) | 2010-10-20 | — | — | EP | claimed |
| EP-1570835-B1 | Composition for the permanent deformation of the hair comprising at least one carboxydithiol | OREAL (FR) | 2010-10-20 | — | — | EP | disclosed |