Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.41 |
| ▸ | FABP7 | O15540 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | MDM4 | O15151 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28773112 | 1.00 | CASP3 (0.41) | CASP3FABP7FABP5MDM4TP53 | |
| SCHEMBL16574596 | 0.95 | CASP3 (0.40) | CASP3FABP7FABP5MDM4TP53 | |
| SCHEMBL23056430 | 0.91 | CASP3 (0.35) | CASP3FABP7FABP5MDM4TP53 | |
| SCHEMBL25658831 | 0.91 | CASP3 (0.35) | CASP3FABP7FABP5MDM4TP53 | |
| SCHEMBL25658838 | 0.91 | CASP3 (0.35) | CASP3FABP7FABP5MDM4TP53 | |
| SCHEMBL28773107 | 0.87 | CASP3 (0.44) | CASP3FABP7FABP5MDM4TP53 | |
| SCHEMBL26666846 | 0.87 | CASP3 (0.44) | CASP3FABP7FABP5MDM4TP53 | |
| SCHEMBL28773045 | 0.85 | CASP3 (0.41) | CASP3FABP7FABP5MDM4TP53 | |
| SCHEMBL29129262 | 0.85 | CASP3 (0.41) | CASP3FABP7FABP5MDM4TP53 | |
| SCHEMBL28773162 | 0.84 | CASP3 (0.42) | CASP3FABP7FABP5MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114729006-A | Cyclic peptide compounds having Kras inhibitory activity | 中外制药株式会社 | 2022-07-08 | — | — | CN | disclosed |