Biphenyl

Biphenyl

SCHEMBL28773145

C=CCCC(=O)O.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.67

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 4/20 0.52
LMNA P02545 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
CYP1A2 P05177 2/20 0.50
RAB9A P51151 1/20 0.50
HIF1A Q16665 1/20 0.50
ALDH1A1 P00352 3/20 0.47
HSD17B10 Q99714 3/20 0.47
KDM4E B2RXH2 1/20 0.47
HPGD P15428 1/20 0.47
KMT2A Q03164 1/20 0.47
ABCC4 O15439 2/20 0.47
MAPT P10636 2/20 0.47
TSHR P16473 2/20 0.45
HTT P42858 2/20 0.45
GAA P10253 1/20 0.45
PTGS1 P23219 1/20 0.45
KEAP1 Q14145 1/20 0.43
PTGER1 P34995 1/20 0.42
PTGER4 P35408 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27669826 0.93 PTGER1 (0.53) FFAR1LMNASMN1; SMN2CYP1A2RAB9A
Benzene SCHEMBL27744162 0.87 MAPT (0.58) FFAR1LMNAALDH1A1HSD17B10KDM4E
Biphenyl SCHEMBL11045970 0.83 LMNA (0.48) FFAR1LMNASMN1; SMN2CYP1A2RAB9A
SCHEMBL115342 0.82
SCHEMBL27871457 0.81 SMN1; SMN2 (0.62) FFAR1LMNASMN1; SMN2CYP1A2RAB9A
Biphenyl SCHEMBL28382562 0.81 FFAR1 (0.57) FFAR1LMNASMN1; SMN2CYP1A2RAB9A
SCHEMBL17491668 0.80 APEX1 (0.41) SMN1; SMN2CYP1A2RAB9AALDH1A1HSD17B10
Ammonia Solution, Strong SCHEMBL10482853 0.79
SCHEMBL1025487 0.79
Hydrochloric Acid SCHEMBL1427875 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101143818-A Enantioselectivity reversion method for allyl substitution reaction catalyzed by Pd UNIV SHANGHAI JIAOTONG (CN) 2008-03-19 CN disclosed