Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | METAP2 | P50579 | 1/20 | 0.49 |
| ▸ | BID | P55957 | 3/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.47 |
| ▸ | KAT8 | Q9H7Z6 | 3/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.47 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.47 |
| ▸ | EP300 | Q09472 | 2/20 | 0.47 |
| ▸ | KAT5 | Q92993 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.47 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.47 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | NCF1 | P14598 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7875801 | 1.00 | KCNH2 (0.59) | KCNH2METAP2BIDMCL1KAT8 | |
| SCHEMBL8898779 | 1.00 | KCNH2 (0.59) | KCNH2METAP2BIDMCL1KAT8 | |
| SCHEMBL10349305 | 1.00 | KCNH2 (0.59) | KCNH2METAP2BIDMCL1KAT8 | |
| SCHEMBL11849124 | 1.00 | KCNH2 (0.59) | KCNH2METAP2BIDMCL1KAT8 | |
| SCHEMBL6051279 | 0.98 | KCNH2 (0.56) | KCNH2METAP2BIDMCL1KAT8 | |
| SCHEMBL1160443 | 0.94 | METAP2 (0.51) | KCNH2METAP2PDE10APLAUNCF1 | |
| SCHEMBL11059362 | 0.92 | F7 (0.53) | KCNH2METAP2BIDMCL1BCL2L1 | |
| SCHEMBL4393939 | 0.90 | METAP2 (0.53) | METAP2PDE10APLAUNCF1ALDH1A1 | |
| SCHEMBL8605536 | 0.89 | BID (0.53) | KCNH2METAP2BIDMCL1BCL2L1 | |
| SCHEMBL2484187 | 0.87 | METAP2 (0.55) | METAP2PDE10APLAUNCF1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063948-A2 | NOVEL C-XYLOSIDE OXIME COMPOUNDS, AND COSMETIC USE | L'OREAL (FR) | 2010-06-10 | — | — | WO | disclosed |