Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2951827 | 0.78 | NLRP3 (0.55) | NLRP3 | |
| SCHEMBL2951820 | 0.78 | NLRP3 (0.55) | NLRP3 | |
| SCHEMBL1567471 | 0.66 | — | — | |
| SCHEMBL29058931 | 0.66 | NLRP3 (0.39) | NLRP3 | |
| SCHEMBL21339578 | 0.65 | POLB (0.34) | NLRP3 | |
| SCHEMBL981868 | 0.65 | POLB (0.34) | NLRP3 | |
| SCHEMBL1867848 | 0.65 | NLRP3 (0.33) | NLRP3 | |
| SCHEMBL21339663 | 0.63 | NPC1 (0.33) | — | |
| SCHEMBL18306706 | 0.63 | NPC1 (0.31) | NLRP3TSHR | |
| SCHEMBL10571332 | 0.62 | NLRP3 (0.45) | NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114409664-B | Spiro heterocyclic tetrahydropyran compound and preparation method and application thereof | 河北威远生物化工有限公司 | 2023-07-18 | — | — | CN | claimed |
| CN-114409664-A | Spiro-heterocyclic tetrahydropyran compound and preparation method and application thereof | 河北威远生物化工有限公司 | 2022-04-29 | — | — | CN | claimed |
| CN-114409664-B | Spiro heterocyclic tetrahydropyran compound and preparation method and application thereof | 河北威远生物化工有限公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-114409664-A | Spiro-heterocyclic tetrahydropyran compound and preparation method and application thereof | 河北威远生物化工有限公司 | 2022-04-29 | — | — | CN | disclosed |