Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1SLC9A3
The experimentally established mechanism targets of Decanoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC11 known ✓ | Q96DB2 | 5/20 | 0.65 |
| ▸ | PDE3A known ✓ | Q14432 | 1/20 | 0.65 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.65 |
| ▸ | PPARG | P37231 | 7/20 | 0.65 |
| ▸ | PPARD | Q03181 | 7/20 | 0.65 |
| ▸ | PPARA | Q07869 | 7/20 | 0.65 |
| ▸ | TSHR | P16473 | 4/20 | 0.65 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | TLR2 | O60603 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | FABP4 | P15090 | 2/20 | 0.65 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.65 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.65 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dodecanoate SCHEMBL8332926 | 1.00 | GPR84 (0.65) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL6652007 | 1.00 | GPR84 (0.65) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octanoic Acid SCHEMBL28450566 | 1.00 | GPR84 (0.65) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL28017066 | 0.98 | GPR84 (0.63) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL27417983 | 0.96 | GPR84 (0.65) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octanoic Acid SCHEMBL526186 | 0.96 | GPR84 (0.65) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL11053142 | 0.96 | GPR84 (0.65) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL27404452 | 0.92 | GPR84 (0.55) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL27280872 | 0.90 | GPR84 (0.57) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL29474870 | 0.86 | GPR84 (0.68) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101198308-B | Foamable alcohol compositions, systems and methods of use | 3M INNOVATIVE PROPERTIES CO | 2013-04-10 | — | — | CN | disclosed |
| CN-101198308-A | Foamable alcohol compositions, systems and methods of use | 3M INNOVATIVE PROPERTIES CO (US) | 2008-06-11 | — | — | CN | disclosed |