Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 16/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 9/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.35 |
| ▸ | BPTF | Q12830 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2869938 | 0.75 | DPP4 (0.36) | DPP4DPP7BPTF | |
| SCHEMBL2877462 | 0.68 | POLB (0.55) | DPP4DPP8DPP7DPP9BPTF | |
| SCHEMBL5789566 | 0.66 | DPP9 (0.60) | DPP4DPP8DPP9 | |
| SCHEMBL5804593 | 0.65 | DPP9 (0.55) | DPP4DPP8DPP9 | |
| SCHEMBL6052795 | 0.64 | — | — | |
| SCHEMBL10611575 | 0.64 | DPP4 (0.47) | DPP4DPP8DPP7DPP9 | |
| Hydrochloric Acid SCHEMBL6162602 | 0.63 | DPP7 (0.51) | DPP4DPP8DPP7DPP9 | |
| Hydrochloric Acid SCHEMBL8552428 | 0.63 | DPP7 (0.51) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL4419351 | 0.63 | DPP4 (0.48) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL11636923 | 0.62 | LMNA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1794120-B1 | PEPTIDASE INHIBITORS | NUADA LLC (US) | 2012-04-11 | — | — | EP | disclosed |
| US-7842707-B2 | Peptidase inhibitors | NUADA, LLC (US) | 2010-11-30 | — | — | US | disclosed |
| US-20080234292-A1 | Such as S)-(1-(1-Aminobicyclo[2.2.2]oct-4-yl)aminoacetyl)-2-cyanopyrrolidine; inhibitors of the enzyme dipeptidyl peptidase; antidiabetic agents | NUADA, LLC | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234292-A1 | Such as S)-(1-(1-Aminobicyclo[2.2.2]oct-4-yl)aminoacetyl)-2-cyanopyrrolidine; inhibitors of the enzyme dipeptidyl peptidase; antidiabetic agents | DPP3, DPP4, DPP7 | DPP4 2/4885DPP8 5/4885DPP7 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.