SCHEMBL28775469

SCHEMBL28775469

NC(=O)OC[C@H]1CCNC[C@@H]1O

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC6A1 P30531 2/20 0.35
GABRA5 P31644 2/20 0.35
GABRB2 P47870 2/20 0.35
SLC6A12 P48065 2/20 0.35
SLC6A11 P48066 2/20 0.35
SLC6A13 Q9NSD5 2/20 0.35
KDM4E B2RXH2 1/20 0.35
MAPT P10636 1/20 0.35
KMT2A Q03164 1/20 0.35
ATM Q13315 1/20 0.35
CYP2D6 P10635 1/20 0.35
GABRA1 P14867 1/20 0.35
GABRR1 P24046 1/20 0.35
GABRA4 P48169 1/20 0.35
ALOX15 P16050 1/20 0.30
MAN1B1 Q9UKM7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28911025 0.83 GBA1 (0.41) ALOX15MAN1B1
Hydrochloric Acid SCHEMBL31157801 0.79 SLC6A1 (0.33) SLC6A1GABRA5GABRB2SLC6A12SLC6A11
SCHEMBL994208 0.78 SLC6A1 (0.41) SLC6A1GABRA5GABRB2SLC6A12SLC6A11
SCHEMBL28249924 0.78 SLC6A1 (0.50) SLC6A1GABRA5GABRB2SLC6A12SLC6A11
SCHEMBL28249888 0.78 SLC6A1 (0.50) SLC6A1GABRA5GABRB2SLC6A12SLC6A11
SCHEMBL994209 0.78 SLC6A1 (0.41) SLC6A1GABRA5GABRB2SLC6A12SLC6A11
SCHEMBL17494202 0.78 SLC6A1 (0.50) SLC6A1GABRA5GABRB2SLC6A12SLC6A11
SCHEMBL994207 0.78 SLC6A1 (0.41) SLC6A1GABRA5GABRB2SLC6A12SLC6A11
SCHEMBL21828115 0.76 CA1 (0.41) ALOX15
SCHEMBL2904780 0.76 GBA1 (0.36) SLC6A1GABRA5GABRB2SLC6A12SLC6A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114728170-A Compounds active on nuclear receptors 纽韦卢森公司 2022-07-08 CN disclosed