Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6283206 | 0.89 | CYP19A1 (0.47) | SIGMAR1KCNH2CHRM2HTR1AADRA2A | |
| SCHEMBL5332634 | 0.89 | HTR2A (0.41) | SIGMAR1KCNH2CHRM2HTR1AADRA2A | |
| SCHEMBL6283212 | 0.87 | KCNH2 (0.48) | SIGMAR1KCNH2CHRM2HTR1AADRA2A | |
| SCHEMBL27464581 | 0.86 | HTR2A (0.59) | SIGMAR1KCNH2CHRM2ADRA2ACHRM1 | |
| SCHEMBL27464580 | 0.86 | HTR2A (0.55) | SIGMAR1KCNH2CHRM2HTR1AADRA2A | |
| SCHEMBL28056319 | 0.85 | CYP19A1 (0.49) | SIGMAR1KCNH2CHRM2HTR1AADRA2A | |
| SCHEMBL2052039 | 0.84 | POLB (0.45) | SIGMAR1OPRM1HTR2A | |
| SCHEMBL1263573 | 0.84 | AOC3 (0.48) | SIGMAR1HTR2A | |
| SCHEMBL10014098 | 0.84 | HTR2A (0.49) | SIGMAR1KCNH2CHRM2HTR1AADRA2A | |
| SCHEMBL5423814 | 0.82 | SIGMAR1 (0.44) | SIGMAR1OPRM1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101282719-A | Glepp-1 inhibitors for the treatment of autoimmune and/or inflammatory diseases | SERONO LAB (CH) | 2008-10-08 | — | — | CN | claimed |