SCHEMBL287763

SCHEMBL287763

COCc1[c]c(Br)cc(C(F)(C(F)(F)F)C(F)(F)C(F)(F)F)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14844593 0.92
SCHEMBL289198 0.84
SCHEMBL288624 0.83
SCHEMBL289477 0.82
SCHEMBL19210169 0.80
SCHEMBL289390 0.79
SCHEMBL288177 0.75 CACNA1H (0.30)
SCHEMBL697739 0.74
SCHEMBL698903 0.74
SCHEMBL14844502 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3339286-A1 INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2018-06-27 EP claimed
US-20120295907-A1 INSECTICIDAL COMPOUNDS SYNGENTA CROP PROTECTION, LLC (US) 2012-11-22 US claimed
EP-2427426-A1 INSECTICIDAL COMPOUNDS Syngenta Participations AG (CH) 2012-03-14 EP claimed
WO-2010127928-A1 INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2010-11-11 WO claimed
EP-3366675-A1 INSECTICIDAL 2-METHOXYBENZAMIDE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2018-08-29 EP disclosed
EP-3339286-A1 INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2018-06-27 EP disclosed
US-9023873-B2 Insecticidal 2-methoxybenzamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2015-05-05 US disclosed
US-20140323528-A1 INSECTICIDAL 2-METHOXYBENZAMIDE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2014-10-30 US disclosed
EP-2763966-A1 INSECTICIDAL 2-METHOXYBENZAMIDE DERIVATIVES Syngenta Participations AG (CH) 2014-08-13 EP disclosed
WO-2013092942-A1 USE OF AMINOBENZAMIDE DERIVATIVES FOR CONTROLLING ANIMAL PARASITES SYNGENTA PARTICIPATIONS AG (CH) 2013-06-27 WO disclosed
WO-2013050261-A1 INSECTICIDAL 2-METHOXYBENZAMIDE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2013-04-11 WO disclosed
US-20120295907-A1 INSECTICIDAL COMPOUNDS SYNGENTA CROP PROTECTION, LLC (US) 2012-11-22 US disclosed
EP-2427426-A1 INSECTICIDAL COMPOUNDS Syngenta Participations AG (CH) 2012-03-14 EP disclosed
WO-2010127928-A1 INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2010-11-11 WO disclosed