SCHEMBL288177

SCHEMBL288177

COCc1[c]c(C)cc(C(F)(C(F)(F)F)C(F)(F)F)c1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CACNA1H O95180 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL289198 0.92
SCHEMBL14844593 0.82
SCHEMBL14844502 0.82
SCHEMBL289831 0.81
SCHEMBL1361657 0.79
SCHEMBL2684564 0.78
SCHEMBL288176 0.78
SCHEMBL289477 0.75
SCHEMBL287763 0.75
SCHEMBL698260 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3339286-A1 INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2018-06-27 EP claimed
EP-2044006-B1 INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2018-05-30 EP claimed
US-20130184343-A1 INSECTICIDAL COMPOUNDS SYNGENTA CROP PROTECTION LLC (US) 2013-07-18 US claimed
US-8420855-B2 Insecticidal compounds SYNGENTA CROP PROTECTION LLC (US) 2013-04-16 US claimed
US-20120295907-A1 INSECTICIDAL COMPOUNDS SYNGENTA CROP PROTECTION, LLC (US) 2012-11-22 US claimed
CN-102414170-A Insecticidal compounds SYNGENTA PARTICIPATIONS AG 2012-04-11 CN claimed
EP-2427426-A1 INSECTICIDAL COMPOUNDS Syngenta Participations AG (CH) 2012-03-14 EP claimed
WO-2010127928-A1 INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2010-11-11 WO claimed
US-20100048715-A1 INSECTICIDAL COMPOUNDS SYNGENTA CROP PROTECTION, INC. (US) 2010-02-25 US claimed
EP-2044006-A1 INSECTICIDAL COMPOUNDS Syngeta Participations AG (CH) 2009-04-08 EP claimed
WO-2008000438-A1 INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2008-01-03 WO claimed
EP-2981523-B1 INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2021-05-19 EP disclosed
EP-2981524-B1 INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2020-05-13 EP disclosed
EP-2914577-B1 INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2020-05-13 EP disclosed
EP-3366675-A1 INSECTICIDAL 2-METHOXYBENZAMIDE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2018-08-29 EP disclosed
WO-2008107091-A1 INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2008-09-12 WO disclosed
WO-2008074427-A1 INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2008-06-26 WO disclosed
EP-1911751-A1 AMIDE DERIVATIVE AND PESTICIDE CONTAINING SUCH COMPOUND Mitsui Chemicals, Inc. (JP) 2008-04-16 EP disclosed
WO-2008031534-A1 INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2008-03-20 WO disclosed
WO-2008000438-A1 INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2008-01-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120295907-A1 INSECTICIDAL COMPOUNDS ACHE, AADAC, BCHE CACNA1H 2826/4885
US-20100048715-A1 INSECTICIDAL COMPOUNDS ACHE, CHRM1, CHRM2 CACNA1H 1426/4885
US-20130184343-A1 INSECTICIDAL COMPOUNDS ACHE, CHRM1, CHRM2 CACNA1H 1432/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.