Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.49 |
| ▸ | KDM5A | P29375 | 1/20 | 0.49 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ADA | P00813 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18081023 | 1.00 | KDM5B (0.49) | KDM5BKDM5APHF8MEN1KMT2A | |
| SCHEMBL21198931 | 0.83 | CYP17A1 (0.49) | KDM5BKDM5ACYP17A1KDM4EALDH1A1 | |
| SCHEMBL18081014 | 0.80 | KDM5B (0.50) | KDM5BKDM5APHF8MEN1KMT2A | |
| SCHEMBL2980379 | 0.79 | PDE2A (0.53) | KDM5B | |
| SCHEMBL20009013 | 0.79 | KDM5B (0.49) | KDM5BKDM5APHF8MEN1KMT2A | |
| SCHEMBL18038826 | 0.79 | KDM5B (0.49) | KDM5BKDM5APHF8MEN1KMT2A | |
| SCHEMBL27744439 | 0.79 | KDM5B (0.49) | KDM5BKDM5APHF8MEN1KMT2A | |
| SCHEMBL27744440 | 0.79 | KDM5B (0.49) | KDM5BKDM5APHF8MEN1KMT2A | |
| SCHEMBL30268927 | 0.78 | KDM5B (0.49) | KDM5BKDM5APHF8MEN1KMT2A | |
| SCHEMBL21199626 | 0.75 | RIPK1 (0.37) | KDM5BCYP17A1ADA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101309687-A | Hydroxy and alkoxy substituted 1h-imidazoquinolines and methods | COLEY PHARM GROUP INC (US) | 2008-11-19 | — | — | CN | disclosed |