SCHEMBL2877649

SCHEMBL2877649

Cc1cn([C@]2(CN)O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]c1=O

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TK1 P04183 5/20 0.43
ALB P02768 2/20 0.40
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
POLB P06746 1/20 0.40
ADRA1A P35348 1/20 0.40
BLM P54132 1/20 0.40
TYMP P19971 2/20 0.38
TK2 O00142 2/20 0.38
PKM P14618 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13387567 0.91 TK1 (0.44) TK1ALBALDH1A1LMNAPOLB
SCHEMBL8053437 0.89 TK1 (0.42) TK1ALBALDH1A1LMNAPOLB
SCHEMBL25191053 0.88 TK1 (0.37) TK1ALBALDH1A1LMNAPOLB
SCHEMBL6753364 0.88 TK1 (0.41) TK1ALBALDH1A1LMNAPOLB
SCHEMBL27878939 0.86 TYMP (0.46) TK1ALBALDH1A1LMNAPOLB
SCHEMBL7025013 0.85 TK1 (0.38) TK1ALBALDH1A1LMNAPOLB
SCHEMBL4342615 0.84 TK1 (0.39) TK1ALBALDH1A1LMNAPOLB
SCHEMBL28182722 0.84 TK2 (0.46) TK1ALBALDH1A1LMNAPOLB
SCHEMBL28190357 0.83 TK2 (0.47) TK1ALBALDH1A1LMNAPOLB
SCHEMBL28942182 0.83 TK2 (0.34) TK1TK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118161602-A RNA for treating autoimmune diseases 生物技术公司 2024-06-11 CN claimed
CN-103328655-A Signal amplification SPEEDX PTY LTD 2013-09-25 CN claimed
CN-120153081-A APLP2 safe harbor site knock-in strategy 埃门多生物公司 2025-06-13 CN disclosed
CN-119789852-A Compositions and methods for delivering RNA 再生技术有限责任公司 2025-04-08 CN disclosed
CN-118786212-A SARM1 expression reduction for cell therapy 埃门多生物公司 2024-10-15 CN disclosed
EP-4433592-A1 COMPOSITIONS AND METHODS FOR PRODUCTION OF CIRCULAR NUCLEIC ACID MOLECULES CIRCULARIS BIOTECHNOLOGIES, INC. (US) 2024-09-25 EP disclosed
CN-118355348-A Hepatitis B Virus (HBV) knockout 埃门多生物公司 2024-07-16 CN disclosed
CN-118234861-A Nucleic acids for inhibiting Complement Factor B (CFB) expression in cells 赛伦斯治疗有限责任公司 2024-06-21 CN disclosed
CN-118161602-A RNA for treating autoimmune diseases 生物技术公司 2024-06-11 CN disclosed
CN-117651771-A TMPRSS6 targeted siRNA for treatment of myeloproliferative disorders 赛伦斯治疗有限责任公司 2024-03-05 CN disclosed
CN-117396193-A Compositions and methods for delivering RNA 再生技术有限责任公司 2024-01-12 CN disclosed
CN-100510101-C Methods and compositions for detecting SARS virus and other infectious agents CAPITALBIO CORP TSINGHUA UNIVE (CN) 2009-07-08 CN disclosed
CN-100480397-C Biochip for detecting SARS virus CAPITALBIO CORP SINGHUA UNIVER (CN) 2009-04-22 CN disclosed
CN-101243316-A Porous composite electrode containing conductive polymer APPLERA CORP (US) 2008-08-13 CN disclosed
WO-2007072221-A2 SURFACE MARKER-DIRECTED CANCER THERAPEUTICS AURELIUM BIOPHARMA INC. (US) 2007-06-28 WO disclosed
CN-1891826-A Gene specifically expressed in postmitotic dopaminergic neuron precursor cells EISAI CO LTD (JP) 2007-01-10 CN disclosed
CN-1816635-A Method for detection of alkylated cytosine in DNA JOHNSON & JOHNSON RES PTY LTD (AU) 2006-08-09 CN disclosed
CN-1802438-A Method and composition for detecting SARS virus CAPITALBIO CORP (CN) 2006-07-12 CN disclosed
CN-1802440-A Methods and compositions for detecting SARS virus and other infectious agents CAPITALBIO CORP (CN) 2006-07-12 CN disclosed
CN-1729290-A Gene specifically expressed in dopamine-producing neuronal precursor cells after division arrest EISAI CO LTD (JP) 2006-02-01 CN disclosed