Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 20/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.64 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | HTR1D | P28221 | 2/20 | 0.48 |
| ▸ | HTR1B | P28222 | 2/20 | 0.48 |
| ▸ | HTR1F | P30939 | 2/20 | 0.48 |
| ▸ | HTR7 | P34969 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27750234 | 0.99 | HTR6 (0.80) | HTR6CYP3A4CYP2D6HTR1AHTR1D | |
| SCHEMBL3621546 | 0.89 | HTR6 (1.00) | HTR6CYP3A4CYP2D6HTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL3622792 | 0.88 | HTR6 (1.00) | HTR6CYP3A4CYP2D6HTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL3204600 | 0.88 | HTR6 (1.00) | HTR6CYP3A4CYP2D6HTR1AHTR1D | |
| SCHEMBL3620088 | 0.85 | HTR6 (0.91) | HTR6CYP3A4CYP2D6HTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL3618986 | 0.84 | HTR6 (0.92) | HTR6CYP3A4CYP2D6HTR1AHTR1D | |
| SCHEMBL3619729 | 0.84 | HTR6 (0.98) | HTR6CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL3265031 | 0.83 | HTR6 (1.00) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL3624597 | 0.81 | HTR6 (0.90) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL3626963 | 0.80 | HTR6 (0.81) | HTR6CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101484420-A | Indoles as 5-HT 6 modulators | BIOVITRUM AB PUBL (SE) | 2009-07-15 | — | — | CN | claimed |
| CN-101484420-A | Indoles as 5-HT 6 modulators | BIOVITRUM AB PUBL (SE) | 2009-07-15 | — | — | CN | disclosed |