Benzamidine

Benzamidine

SCHEMBL2877747

N.N=C(N)c1ccccc1

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 3/20 0.94
F10 P00742 1/20 0.94
F12 P00748 1/20 0.94
F7 P08709 1/20 0.94
F3 P13726 1/20 0.94
PKM P14618 1/20 0.94
BLM P54132 2/20 0.89
PRSS1 P07477 4/20 0.84
PRSS3 P35030 4/20 0.84
PRSS2 P07478 3/20 0.84
C1S P09871 2/20 0.84
RECQL P46063 2/20 0.84
KMT2A Q03164 1/20 0.84
WDR5 P61964 1/20 0.68
LMNA P02545 2/20 0.55
PLAU P00749 2/20 0.55
MASP2 O00187 1/20 0.55
THPO P40225 1/20 0.55
NQO2 P16083 2/20 0.54
APEX1 P27695 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzamidine SCHEMBL27781057 0.97 F2 (1.00) F2F10F12F7F3
Benzamidine SCHEMBL23067876 0.97 F2 (1.00) F2F10F12F7F3
SCHEMBL18557033 0.97 F2 (1.00) F2F10F12F7F3
Benzamidine SCHEMBL9207 0.97
Benzamidine SCHEMBL6861235 0.94 BLM (1.00) F2F10F12F7F3
Benzamidine SCHEMBL7103811 0.94 F2 (0.94) F2F10F12F7F3
Benzamidine SCHEMBL28513704 0.94 F2 (0.94) F2F10F12F7F3
Benzamidine SCHEMBL23235801 0.94 BLM (1.00) F2F10F12F7F3
Benzamidine SCHEMBL5494618 0.94 F2 (0.94) F2F10F12F7F3
Benzamidine SCHEMBL31530552 0.94 F2 (0.94) F2F10F12F7F3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105330568-B Preparation method for p-aminobenzamidine hydrochloride 山东省医学科学院药物研究所 2017-05-10 CN claimed
CN-109475354-A Multi-chamber devices ADN国际有限公司 2019-03-15 CN disclosed
CN-105330568-B Preparation method for p-aminobenzamidine hydrochloride 山东省医学科学院药物研究所 2017-05-10 CN disclosed
CN-102917690-B Lipid vesicle composition and using method 麻省理工学院 2016-08-24 CN disclosed
CN-101163717-B Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases HALOZYME INC 2014-06-25 CN disclosed
CN-202662374-U Rat-proof, termite-proof, flame-retardant and environment-friendly power cable JIANGSU HAIDA ELECTRIC CABLE CO LTD 2013-01-09 CN disclosed
CN-102708983-A Anti-rat, anti-termite, flame-retardant and environmentally friendly power cable JIANGSU HAIDA ELECTRIC CABLE CO LTD 2012-10-03 CN disclosed
CN-101005828-B Compositions comprising a mucoadhesive protein and an active principle for mucosal delivery of said agents VIRUN INC 2012-01-11 CN disclosed
WO-2010083501-A2 ALPHA-HELIX MIMETIC USING A 2,5-OLIGOPYRIMIDINE SCAFFOLD UNIVERSITY OF SOUTH FLORIDA (US) 2010-07-22 WO disclosed
CN-101784274-A The method and composition that suppresses edema factor and adenyl cyclase MISSION PHARMA CO 2010-07-21 CN disclosed
CN-101163717-A Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases HALOZYME THERAPEUTICS INC (US) 2008-04-16 CN disclosed
CN-101005828-A Compositions comprising a mucoadhesive protein and an activeprinciple for mucosal delivery of said agents VIRUN INC (US) 2007-07-25 CN disclosed