SCHEMBL28777664 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	JAK1	P23458	5/20	0.36

▸	JAK2	O60674	4/20	0.35

▸	AXL	P30530	4/20	0.35

▸	PIK3CD	O00329	1/20	0.35

▸	TYRO3	Q06418	1/20	0.35

▸	MERTK	Q12866	1/20	0.35

▸	CSNK1E	P49674	1/20	0.34

▸	RET	P07949	1/20	0.33

▸	ALOX5AP	P20292	7/20	0.33

▸	FEN1	P39748	7/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL28777665	1.00	JAK1 (0.36)	JAK1JAK2AXLPIK3CDTYRO3
SCHEMBL28777660	1.00	JAK1 (0.36)	JAK1JAK2AXLPIK3CDTYRO3
SCHEMBL22976454	0.88	JAK2 (0.38)	JAK1JAK2AXLPIK3CDTYRO3
SCHEMBL22976139	0.88	JAK2 (0.38)	JAK1JAK2AXLPIK3CDTYRO3
SCHEMBL22976138	0.88	JAK2 (0.38)	JAK1JAK2AXLPIK3CDTYRO3
SCHEMBL22976361	0.88	JAK2 (0.38)	JAK1JAK2AXLPIK3CDTYRO3
SCHEMBL29720010	0.88	JAK2 (0.38)	JAK1JAK2AXLPIK3CDTYRO3
SCHEMBL28777487	0.86	CYP11B2 (0.35)	RET
SCHEMBL28777484	0.86	CYP11B2 (0.35)	RET
SCHEMBL28777488	0.86	CYP11B2 (0.35)	RET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-114585614-A	Non-peptide somatostatin type 5 receptor agonists and uses thereof	克林提克斯医药股份有限公司	2022-06-03	—	—	CN	disclosed