Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | LPO | P22079 | 2/20 | 0.69 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | TAS2R38 | P59533 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MPO | P05164 | 2/20 | 0.39 |
| ▸ | TPO | P07202 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | CYB5R3 | P00387 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL28777755 | 1.00 | SMN1; SMN2 (0.69) | SMN1; SMN2LPOPTGS1CYP2C19BAZ2B | |
| Methylthiouracil SCHEMBL159989 | 0.83 | — | — | |
| Methylthiouracil SCHEMBL5798462 | 0.81 | SMN1; SMN2 (0.95) | SMN1; SMN2LPOPTGS1CYP2C19BAZ2B | |
| Cadaverine Tartrate SCHEMBL161288 | 0.62 | TSHR (0.91) | CYP2C19LMNATSHRMAPTKMT2A | |
| Cadaverine Tartrate SCHEMBL11605987 | 0.62 | TSHR (0.91) | CYP2C19LMNATSHRMAPTKMT2A | |
| Cadaverine Tartrate SCHEMBL28055270 | 0.61 | TSHR (0.56) | SMN1; SMN2LMNAGAATSHRMAPT | |
| SCHEMBL14217392 | 0.61 | — | — | |
| Cadaverine Tartrate SCHEMBL8945831 | 0.59 | TSHR (0.83) | CYP2C19LMNATSHRMAPTKMT2A | |
| Cadaverine Tartrate SCHEMBL950956 | 0.59 | TSHR (0.83) | CYP2C19LMNATSHRKMT2AALDH1A1 | |
| Cadaverine Tartrate SCHEMBL9763204 | 0.59 | TSHR (0.83) | CYP2C19LMNATSHRKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114585620-A | Oxadiazole compound or salt thereof, agricultural/horticultural fungicide containing the same, and method for using the same | 日本农药株式会社 | 2022-06-03 | — | — | CN | disclosed |
| CN-114008045-A | Agrohorticultural agent containing novel imidazopyridine-2-carboxamide derivative as active ingredient | 阿格罗－金正株式会社 | 2022-02-01 | — | — | CN | disclosed |