Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3909608 | 0.83 | SCN9A (0.43) | ADRA2CCHRNB2CHRNA4GAA | |
| SCHEMBL3909612 | 0.83 | SCN9A (0.43) | ADRA2CCHRNB2CHRNA4GAA | |
| SCHEMBL432319 | 0.82 | SMN1; SMN2 (0.51) | KMT2ASMN1; SMN2MAPTALDH1A1NOTUM | |
| SCHEMBL630857 | 0.82 | SMN1; SMN2 (0.51) | KMT2ASMN1; SMN2MAPTALDH1A1NOTUM | |
| SCHEMBL15664724 | 0.82 | SMN1; SMN2 (0.51) | KMT2ASMN1; SMN2MAPTALDH1A1NOTUM | |
| SCHEMBL11985529 | 0.82 | SMN1; SMN2 (0.43) | KMT2ASMN1; SMN2MAPTSERPINE1HSD11B1 | |
| SCHEMBL3450033 | 0.82 | SMN1; SMN2 (0.43) | KMT2ASMN1; SMN2MAPTSERPINE1HSD11B1 | |
| SCHEMBL3450292 | 0.82 | SMN1; SMN2 (0.43) | KMT2ASMN1; SMN2MAPTSERPINE1HSD11B1 | |
| SCHEMBL11983557 | 0.82 | SMN1; SMN2 (0.43) | KMT2ASMN1; SMN2MAPTSERPINE1HSD11B1 | |
| SCHEMBL4715449 | 0.81 | SMN1; SMN2 (0.44) | KMT2ASMN1; SMN2MAPTALDH1A1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114599389-A | Variant FC domains and uses thereof | 奇达拉治疗公司 | 2022-06-07 | — | — | CN | disclosed |