Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | BRS3 | P32247 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
| ▸ | PORCN | Q9H237 | 2/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13015198 | 0.90 | GFER (0.41) | MAPTBRS3KMT2AALDH1A1CASP6 | |
| SCHEMBL7035832 | 0.90 | GFER (0.41) | MAPTBRS3KMT2AALDH1A1CASP6 | |
| SCHEMBL77156 | 0.87 | SYK (0.46) | GFER | |
| SCHEMBL13723813 | 0.87 | SYK (0.46) | GFER | |
| SCHEMBL25262222 | 0.85 | TDP1 (0.45) | SMN1; SMN2MAPTBRS3KMT2AALDH1A1 | |
| SCHEMBL432319 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTKMT2AALDH1A1FFAR1 | |
| SCHEMBL15664724 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTKMT2AALDH1A1FFAR1 | |
| SCHEMBL630857 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTKMT2AALDH1A1FFAR1 | |
| SCHEMBL3060271 | 0.83 | SMN1; SMN2 (0.44) | SMN1; SMN2MAPTBRS3KMT2AALDH1A1 | |
| SCHEMBL9104214 | 0.83 | FFAR1 (0.53) | SMN1; SMN2MAPTFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0964864-B1 | PYRIDO 2,3-D PYRIMIDINES AND 4-AMINOPYRIMIDINES AS INHIBITORS OF CELLULAR PROLIFERATION | WARNER LAMBERT CO (US) | 2008-04-09 | — | — | EP | disclosed |