Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29557803 | 0.93 | HTR2C (0.39) | HTR2CHIF1ANPSR1RXFP1AGTR1 | |
| SCHEMBL24416952 | 0.93 | HTR2C (0.39) | HTR2CHIF1ANPSR1RXFP1AGTR1 | |
| SCHEMBL29557035 | 0.92 | HTR2C (0.38) | HTR2CHIF1ANPSR1RXFP1AGTR1 | |
| SCHEMBL24416911 | 0.92 | HTR2C (0.38) | HTR2CHIF1ANPSR1RXFP1AGTR1 | |
| SCHEMBL29557203 | 0.83 | HIF1A (0.46) | HTR2CHIF1ANPSR1RXFP1ALDH1A1 | |
| SCHEMBL24416859 | 0.83 | HIF1A (0.46) | HTR2CHIF1ANPSR1RXFP1ALDH1A1 | |
| SCHEMBL24416928 | 0.83 | CYP11B1 (0.36) | KCNN4ALDH1A1SMN1; SMN2 | |
| SCHEMBL29557232 | 0.83 | CYP11B1 (0.36) | KCNN4ALDH1A1SMN1; SMN2 | |
| SCHEMBL24416921 | 0.83 | SMN1; SMN2 (0.41) | HTR2CALDH1A1SMN1; SMN2 | |
| SCHEMBL29557394 | 0.83 | SMN1; SMN2 (0.41) | HTR2CALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022095965-A1 | TETRAZOLE DERIVATIVE, PREPARATION FOR TETRAZOLE DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING TETRAZOLE DERIVATIVE, AND APPLICATION OF TETRAZOLE DERIVATIVE | 浙江大学 | 2022-05-12 | — | — | WO | claimed |
| CN-114436985-A | Tetrazole derivative, preparation method thereof, pharmaceutical composition containing tetrazole derivative and application of pharmaceutical composition | 浙江大学 | 2022-05-06 | — | — | CN | claimed |
| WO-2022095965-A1 | TETRAZOLE DERIVATIVE, PREPARATION FOR TETRAZOLE DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING TETRAZOLE DERIVATIVE, AND APPLICATION OF TETRAZOLE DERIVATIVE | 浙江大学 | 2022-05-12 | — | — | WO | disclosed |
| CN-114436985-A | Tetrazole derivative, preparation method thereof, pharmaceutical composition containing tetrazole derivative and application of pharmaceutical composition | 浙江大学 | 2022-05-06 | — | — | CN | disclosed |