SCHEMBL28778338

SCHEMBL28778338

CCCCCCCCCCCCn1c2ccccc2c2cccc(-c3ccccc3)c21

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.54
MAPT P10636 1/20 0.54
PSEN1 P49768 8/20 0.49
PSEN2 P49810 8/20 0.49
APH1B Q8WW43 8/20 0.49
NCSTN Q92542 8/20 0.49
APH1A Q96BI3 8/20 0.49
PSENEN Q9NZ42 8/20 0.49
PGR P06401 1/20 0.48
RORA P35398 1/20 0.48
RORC P51449 1/20 0.48
RORB Q92753 1/20 0.48
CNR2 P34972 5/20 0.47
CNR1 P21554 2/20 0.47
ALDH1A1 P00352 1/20 0.47
HTT P42858 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
GRIN1 Q05586 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28590236 1.00 KDM4E (0.54) KDM4EMAPTPSEN1PSEN2APH1B
SCHEMBL28042024 1.00 KDM4E (0.54) KDM4EMAPTPSEN1PSEN2APH1B
SCHEMBL6280030 0.88 KDM4E (0.50) KDM4EMAPTPGRRORARORC
SCHEMBL17775036 0.84 PGR (0.57) KDM4EMAPTPSEN1PSEN2APH1B
Biphenyl SCHEMBL28481359 0.84 KDM4E (0.63) KDM4EMAPTPSEN1PSEN2APH1B
SCHEMBL17775031 0.84 PGR (0.57) KDM4EMAPTPSEN1PSEN2APH1B
SCHEMBL17775032 0.84 PGR (0.57) KDM4EMAPTPSEN1PSEN2APH1B
SCHEMBL27900579 0.82 KDM4E (0.49) KDM4EMAPTPGRALDH1A1HTT
SCHEMBL15667726 0.82 PGR (0.58) KDM4EMAPTPSEN1PSEN2APH1B
Benzene SCHEMBL28478449 0.82 CNR2 (0.62) KDM4EMAPTPSEN1PSEN2APH1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114621600-B Organic fluorescent dye responding to thermal stimulus and preparation and application thereof 太原理工大学 2023-08-15 CN claimed
CN-114621600-A Thermal stimulation response organic fluorescent dye and preparation and application thereof 太原理工大学 2022-06-14 CN claimed
CN-114621600-B Organic fluorescent dye responding to thermal stimulus and preparation and application thereof 太原理工大学 2023-08-15 CN disclosed
CN-114621600-A Thermal stimulation response organic fluorescent dye and preparation and application thereof 太原理工大学 2022-06-14 CN disclosed