Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 2/20 | 0.47 |
| ▸ | JAK3 | P52333 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL340760 | 0.75 | JAK3 (0.55) | JAK1JAK3MEN1KMT2APKM | |
| SCHEMBL29609678 | 0.73 | JAK3 (0.51) | JAK1JAK3MEN1KMT2APKM | |
| SCHEMBL340050 | 0.73 | JAK3 (0.67) | JAK1JAK3MEN1KMT2APKM | |
| SCHEMBL341507 | 0.71 | JAK3 (0.61) | JAK1JAK3MEN1KMT2APKM | |
| SCHEMBL339033 | 0.70 | GLO1 (0.57) | JAK1JAK3MEN1KMT2APKM | |
| SCHEMBL341465 | 0.69 | JAK3 (0.58) | JAK1JAK3MEN1KMT2APKM | |
| SCHEMBL339032 | 0.69 | JAK1 (0.62) | JAK1JAK3MEN1KMT2APKM | |
| SCHEMBL340759 | 0.69 | JAK1 (0.70) | JAK1JAK3PKMLMNATP53 | |
| SCHEMBL339296 | 0.68 | JAK3 (0.74) | JAK1JAK3MEN1KMT2APKM | |
| SCHEMBL341532 | 0.68 | JAK3 (0.55) | JAK1JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114698370-A | Compounds and methods for treating cytokine release syndrome | 里格尔药品股份有限公司 | 2022-07-01 | — | — | CN | disclosed |