Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | USP2 | O75604 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2868478 | 0.85 | USP2 (0.59) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL20145307 | 0.85 | TSHR (0.59) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL2876943 | 0.85 | ALDH1A1 (0.48) | TSHRUSP2MEN1ALDH1A1MAPT | |
| SCHEMBL18638423 | 0.85 | TSHR (0.59) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL18664262 | 0.85 | TSHR (0.59) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL2880184 | 0.84 | ALDH1A1 (0.56) | TSHRUSP2MEN1ALDH1A1MAPT | |
| SCHEMBL2875019 | 0.81 | USP2 (0.45) | TSHRUSP2MEN1ALDH1A1MAPT | |
| SCHEMBL2876900 | 0.81 | TSHR (0.46) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL2873885 | 0.80 | USP2 (0.44) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL15478713 | 0.80 | HDAC1 (0.49) | HDAC7HDAC8HDAC6HDAC9HDAC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1570835-B1 | Composition for the permanent deformation of the hair comprising at least one carboxydithiol | OREAL (FR) | 2010-10-20 | — | — | EP | claimed |
| EP-1570835-B1 | Composition for the permanent deformation of the hair comprising at least one carboxydithiol | OREAL (FR) | 2010-10-20 | — | — | EP | disclosed |