Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.43 |
| ▸ | RORC | P51449 | 5/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13108620 | 1.00 | AR (0.43) | ARRORCSLC22A12ALDH1A1LMNA | |
| SCHEMBL27777719 | 0.90 | AR (0.40) | ARRORCSLC22A12ALDH1A1LMNA | |
| SCHEMBL12345110 | 0.90 | AR (0.40) | ARRORCSLC22A12ALDH1A1LMNA | |
| SCHEMBL27756886 | 0.89 | AR (0.40) | ARRORCSLC22A12ALDH1A1LMNA | |
| SCHEMBL13108623 | 0.89 | AR (0.40) | ARRORCSLC22A12ALDH1A1LMNA | |
| SCHEMBL12345120 | 0.88 | RORC (0.40) | ARRORCSLC22A12ALDH1A1LMNA | |
| SCHEMBL13108596 | 0.88 | AAK1 (0.37) | ARALDH1A1GAA | |
| SCHEMBL27777714 | 0.87 | RORC (0.40) | ARRORCSLC22A12ALDH1A1LMNA | |
| SCHEMBL13108632 | 0.87 | RORC (0.40) | ARRORCSLC22A12ALDH1A1LMNA | |
| SCHEMBL13108640 | 0.86 | RORC (0.39) | ARRORCSLC22A12ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101522190-A | Pyrrolidinone anilines as progesterone receptor modulators | SMITHKLINE BEECHAM CORP (US) | 2009-09-02 | — | — | CN | disclosed |