Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL226265 | 0.82 | ALDH1A1 (0.54) | SLC18A3ALDH1A1GAASMN1; SMN2HSD17B10 | |
| SCHEMBL27766933 | 0.80 | BRD4 (0.43) | ALDH1A1GAASMN1; SMN2HSD17B10POLB | |
| SCHEMBL27758360 | 0.78 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2LMNAPOLB | |
| SCHEMBL28779356 | 0.78 | DAO (0.37) | ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL3604589 | 0.78 | KMT2A (0.54) | SLC18A3ALDH1A1 | |
| SCHEMBL1697221 | 0.77 | ALDH1A1 (0.62) | SLC18A3ALDH1A1GAASMN1; SMN2HSD17B10 | |
| SCHEMBL27758369 | 0.77 | STS (0.36) | ALDH1A1GAANR2F2NPSR1LMNA | |
| SCHEMBL621714 | 0.76 | ALDH1A1 (0.58) | SLC18A3ALDH1A1GAASMN1; SMN2HSD17B10 | |
| SCHEMBL5960277 | 0.76 | ALDH1A1 (0.68) | SLC18A3ALDH1A1GAASMN1; SMN2HSD17B10 | |
| SCHEMBL28975852 | 0.75 | ALDH1A1 (0.43) | ALDH1A1GAAHSD17B10NR2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101384581-B | Benzoyl-piperidine derivatives as 5HT2/D3 modulators | HOFFMANN LA ROCHE | 2013-09-18 | — | — | CN | disclosed |
| CN-101384581-A | Benzoyl-piperidine derivatives as 5HT2/D3 modulators | HOFFMANN LA ROCHE (CH) | 2009-03-11 | — | — | CN | disclosed |