Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL298254 | 0.77 | TSHR (0.68) | TSHRALDH1A1SMN1; SMN2TDP1HPGD | |
| SCHEMBL1370917 | 0.76 | — | — | |
| SCHEMBL10010571 | 0.75 | TSHR (0.67) | TSHRALDH1A1SMN1; SMN2TDP1HPGD | |
| SCHEMBL4675666 | 0.75 | TSHR (0.67) | TSHRALDH1A1SMN1; SMN2TDP1HPGD | |
| SCHEMBL1373745 | 0.75 | TSHR (0.67) | TSHRALDH1A1SMN1; SMN2TDP1HPGD | |
| SCHEMBL10010574 | 0.75 | TSHR (0.67) | TSHRALDH1A1SMN1; SMN2TDP1HPGD | |
| SCHEMBL28779486 | 0.72 | TSHR (0.38) | TSHRALDH1A1SMN1; SMN2TDP1HPGD | |
| SCHEMBL16048460 | 0.72 | TSHR (0.62) | TSHRALDH1A1SMN1; SMN2TDP1HPGD | |
| SCHEMBL11509921 | 0.72 | TSHR (0.62) | TSHRALDH1A1SMN1; SMN2TDP1HPGD | |
| SCHEMBL20061887 | 0.71 | TSHR (0.61) | TSHRALDH1A1SMN1; SMN2TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591217-B | Preparation method of 6, 6-dimethyl-3-azabicyclo- [3.1.0] -hexane and lactone intermediate thereof | 浙江新和成股份有限公司 | 2024-04-16 | — | — | CN | disclosed |
| CN-114591217-A | Process for the preparation of 6, 6-dimethyl-3-azabicyclo- [3.1.0] -hexane and lactone intermediates thereof | 浙江新和成股份有限公司 | 2022-06-07 | — | — | CN | disclosed |