SCHEMBL298254

SCHEMBL298254

CC(C)COC(=O)C(=O)OCC(C)C

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.68
ALDH1A1 P00352 6/20 0.48
SMN1; SMN2 Q16637 2/20 0.39
TDP1 Q9NUW8 3/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
RAB9A P51151 1/20 0.37
P2RX4 Q99571 1/20 0.37
HPGD P15428 1/20 0.37
KDM4E B2RXH2 2/20 0.36
MAPT P10636 1/20 0.36
MAPK1 P28482 1/20 0.36
HSD17B10 Q99714 1/20 0.36
MEN1 O00255 1/20 0.36
LMNA P02545 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
NFKB1 P19838 1/20 0.36
PTGS1 P23219 1/20 0.36
APEX1 P27695 1/20 0.36
THPO P40225 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31675150 0.89 TSHR (0.58) TSHRALDH1A1SMN1; SMN2MAPTHSD17B10
SCHEMBL11509921 0.88 TSHR (0.62) TSHRALDH1A1SMN1; SMN2TDP1L3MBTL1
SCHEMBL16048460 0.88 TSHR (0.62) TSHRALDH1A1SMN1; SMN2TDP1L3MBTL1
SCHEMBL629560 0.87 TSHR (0.56) TSHRALDH1A1SMN1; SMN2TDP1L3MBTL1
SCHEMBL4675666 0.86 TSHR (0.67) TSHRALDH1A1SMN1; SMN2TDP1L3MBTL1
SCHEMBL10010574 0.86 TSHR (0.67) TSHRALDH1A1SMN1; SMN2TDP1L3MBTL1
SCHEMBL10010571 0.86 TSHR (0.67) TSHRALDH1A1SMN1; SMN2TDP1L3MBTL1
SCHEMBL5314281 0.86 TSHR (0.60) TSHRALDH1A1SMN1; SMN2TDP1L3MBTL1
SCHEMBL1373745 0.86 TSHR (0.67) TSHRALDH1A1SMN1; SMN2TDP1L3MBTL1
SCHEMBL14890738 0.84 TSHR (0.58) TSHRALDH1A1SMN1; SMN2TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 382 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119656881-B Reverse osmosis membrane with coralloid structure and preparation method and application thereof 苏州实验室 2025-05-23 CN claimed
CN-119656881-A Reverse osmosis membrane with coralloid structure and preparation method and application thereof 苏州实验室 2025-03-21 CN claimed
CN-119350607-A Preparation method of high molecular weight poly (alkyl oxalate) homopolymer and copolymer 青岛科技大学 2025-01-24 CN claimed
CN-116253872-B High-temperature-resistant polyamide resin and preparation method thereof 上海凯赛生物技术股份有限公司 2024-10-29 CN claimed
CN-118667148-A Polyamide resin and preparation method thereof 上海凯赛生物技术股份有限公司 2024-09-20 CN claimed
CN-118562538-A Mixed fuel suitable for diesel engine and preparation method thereof 中国汽车技术研究中心有限公司 2024-08-30 CN claimed
CN-115926150-B Polyamide resin and preparation method thereof 上海凯赛生物技术股份有限公司 2024-07-09 CN claimed
CN-116768795-A Synthesis method of cyenopyrafen intermediate 湖南速博生物技术有限公司 2023-09-19 CN claimed
CN-116253872-A High-temperature-resistant polyamide resin and preparation method thereof 上海凯赛生物技术股份有限公司 2023-06-13 CN claimed
CN-115975684-A Vehicle diesel oil for low-temperature quick start of engine and preparation method thereof 山东京博新能源控股发展有限公司 2023-04-18 CN claimed
CN-103172853-A Aliphatic polyamide resin and application thereof DONGLI FIBER INSTUTITE CHINA 2013-06-26 CN claimed
EP-2460560-A1 Hydroalcoholic gel compositions for use with dispensers Gojo Industries, Inc. (US) 2012-06-06 EP claimed
EP-2288416-B1 HYDROALCOHOLIC GEL COMPOSITIONS FOR USE WITH DISPENSERS GOJO IND INC (US) 2012-02-29 EP claimed
CN-102123764-A Hydroalcoholic gel compositions for use with dispensers GOJO IND INC 2011-07-13 CN claimed
US-20110144214-A1 HYDROALCOHOLIC GEL COMPOSITIONS FOR USE WITH DISPENSERS SILVER POINT FINANCE, LLC, AS COLLATERAL AGENT 2011-06-16 US claimed
EP-2288416-A2 HYDROALCOHOLIC GEL COMPOSITIONS FOR USE WITH DISPENSERS GOJO Industries, Inc. (US) 2011-03-02 EP claimed
EP-2097065-A2 FOAMABLE WATERLESS COMPOSITIONS WITH MODULATING AGENTS Foamix Ltd. (IL) 2009-09-09 EP claimed
WO-2009058802-A2 HYDROALCOHOLIC GEL COMPOSITIONS FOR USE WITH DISPENSERS GOJO INDUSTRIES, INC. (US) 2009-05-07 WO claimed
WO-2008152444-A2 FOAMABLE WATERLESS COMPOSITIONS WITH MODULATING AGENTS FOAMIX LTD. (US) 2008-12-18 WO claimed
US-20080206159-A1 Drug mixture contains solvents, nonionic surfactants, gelling agent, therapeutic active agent, liquefied or compressed gas propellant; pressurized dispenser; treating skin diseases, dermal and mucosal delivery; stable and non-irritating emulsions FOAMIX LTD. (IL) 2008-08-28 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110144214-A1 HYDROALCOHOLIC GEL COMPOSITIONS FOR USE WITH DISPENSERS ADH1A, ADH1C, ADH5 TSHR 4450/4885ALDH1A1 47/4885SMN1; SMN2 4316/4885
US-20080206159-A1 Drug mixture contains solvents, nonionic surfactants, gelling agent, therapeutic active agent, liquefied or compressed gas propellant; pressurized dispenser; treating skin diseases, dermal and mucosal delivery; stable and non-irritating emulsions CUTA, SLTM, SMO TSHR 4100/4885ALDH1A1 3777/4885SMN1; SMN2 2112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.