Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | STS | P08842 | 5/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL337418 | 0.85 | ALDH1A1 (0.65) | HPGDGAARECQLPTPN2PTPN1 | |
| SCHEMBL14698843 | 0.85 | HPGD (0.46) | HPGDGAARECQLPTPN2PTPN1 | |
| SCHEMBL20428017 | 0.84 | HPGD (0.45) | HPGDGAARECQLPTPN2PTPN1 | |
| SCHEMBL31706334 | 0.83 | KMT2A (0.58) | HPGDGAARECQLPTPN2PTPN1 | |
| SCHEMBL15878573 | 0.82 | HPGD (0.55) | HPGDGAARECQLPTPN2PTPN1 | |
| SCHEMBL13459039 | 0.82 | HPGD (0.55) | HPGDGAARECQLPTPN2PTPN1 | |
| SCHEMBL4034044 | 0.80 | GAA (0.61) | HPGDGAARECQLKMT2AALDH1A1 | |
| SCHEMBL6643493 | 0.80 | ALDH1A1 (0.60) | HPGDGAARECQLPTPN2PTPN1 | |
| SCHEMBL583783 | 0.80 | HPGD (0.52) | HPGDGAARECQLPTPN2PTPN1 | |
| SCHEMBL634024 | 0.80 | ALDH1A1 (0.60) | HPGDGAARECQLKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101516874-A | Pyrrole derivatives for the treatment of cytokine mediated diseases | NOVARTIS AG (CH) | 2009-08-26 | — | — | CN | disclosed |