Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.35 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.35 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | DTYMK | P23919 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28779849 | 1.00 | IKBKB (0.44) | IKBKBALDH1A1MEN1KMT2APDE4B | |
| SCHEMBL29766740 | 0.90 | IKBKB (0.43) | IKBKBALDH1A1MEN1KMT2APDE4B | |
| SCHEMBL31510002 | 0.83 | DTYMK (0.39) | ALDH1A1MEN1KMT2AKDM4EDTYMK | |
| SCHEMBL28983510 | 0.82 | GPR119 (0.45) | ALDH1A1PDE4BLMNAMAPT | |
| SCHEMBL28779854 | 0.82 | IKBKB (0.47) | IKBKBALDH1A1PDE4BPIK3CDPIK3CA | |
| SCHEMBL28779859 | 0.82 | IKBKB (0.47) | IKBKBALDH1A1PDE4BPIK3CDPIK3CA | |
| SCHEMBL21585616 | 0.77 | SMN1; SMN2 (0.47) | MEN1KMT2APDE4BHTTLMNA | |
| SCHEMBL28779919 | 0.77 | PDE4D (0.37) | PDE4BDTYMK | |
| SCHEMBL28779916 | 0.77 | PDE4D (0.37) | PDE4BDTYMK | |
| SCHEMBL29766769 | 0.74 | IKBKB (0.46) | IKBKBALDH1A1MEN1KMT2APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114716477-A | 7-substituted phosphoryl quinazoline derivative and preparation method and application thereof | 武汉人福创新药物研发中心有限公司 | 2022-07-08 | — | — | CN | disclosed |