⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14052659 | 1.00 | — | — | |
| SCHEMBL6445897 | 0.77 | — | — | |
| SCHEMBL2190608 | 0.75 | — | — | |
| SCHEMBL15637781 | 0.75 | — | — | |
| SCHEMBL127300 | 0.73 | TSHR (0.38) | — | |
| SCHEMBL3936677 | 0.73 | — | — | |
| SCHEMBL851726 | 0.71 | — | — | |
| SCHEMBL9846434 | 0.71 | — | — | |
| SCHEMBL10717249 | 0.69 | — | — | |
| SCHEMBL11111398 | 0.69 | TSHR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2807170-B1 | PHRAGMALIN LIMONOIDS FOR THE TREATMENT OF SEXUAL DYSFUNCTION | DICOT AB (SE) | 2019-03-13 | — | — | EP | claimed |
| EP-3030246-A1 | MICROWAVE STERILIZATION OF PHARMACEUTICAL CYANOACRYLATE ESTERS COMPOSITIONS | Covidien LP (US) | 2016-06-15 | — | — | EP | claimed |
| WO-2015021179-A1 | MICROWAVE STERILIZATION OF PHARMACEUTICAL CYANOACRYLATE ESTERS COMPOSITIONS | SAPHEON, INC. (US) | 2015-02-12 | — | — | WO | claimed |
| US-20150011616-A1 | PHRAGAMALIN LIMONOIDS FOR THE TREATMENT OF SEXUAL DYSFUNCTION | DICOT PHARMA AB (SE) | 2015-01-08 | — | — | US | claimed |
| EP-2807170-A2 | PHRAGAMALIN LIMONOIDS FOR THE TREATMENT OF SEXUAL DYSFUNCTION | Dicotyledon AB (SE) | 2014-12-03 | — | — | EP | claimed |
| WO-2013110744-A2 | NOVEL COMPOUNDS, THEIR MANUFACTURE AND USES (II) | DICOTYLEDON AB (SE) | 2013-08-01 | — | — | WO | claimed |
| US-4173640-A | Hypotensive perhydro naphthalene pentol derivatives | E. R. SQUIBB & SONS, INC. (US) | 1979-11-06 | — | — | US | claimed |
| US-11313866-B2 | Method of diagnosing and treating asphyxia | INFANDX AG (DE) | 2022-04-26 | — | — | US | disclosed |
| CN-108026049-B | Compositions and methods for treating and preventing neurodegenerative disorders | 阿尔泽恩股份有限公司 | 2021-08-31 | — | — | CN | disclosed |
| EP-2807170-B1 | PHRAGMALIN LIMONOIDS FOR THE TREATMENT OF SEXUAL DYSFUNCTION | DICOT AB (SE) | 2019-03-13 | — | — | EP | disclosed |
| US-20180011111-A1 | Method of Diagnosing and Treating Asphyxia | INFANDX AG (DE) | 2018-01-11 | — | — | US | disclosed |
| US-9791459-B2 | Method of diagnosing and treating asphyxia | INFANDX AG (DE) | 2017-10-17 | — | — | US | disclosed |
| US-9403841-B2 | Phragamalin limonoids for the treatment of sexual dysfunction | DICOTYLEDON AB (SE) | 2016-08-02 | — | — | US | disclosed |
| US-4138497-A | Indanpentol derivatives for treating hypertension | E. R. SQUIBB & SONS, INC. (US) | 1979-02-06 | — | — | US | disclosed |
| US-4127578-A | Diene intermediates for indantetrols | E. R. SQUIBB & SONS, INC. (US) | 1978-11-28 | — | — | US | disclosed |
| US-4113726-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1978-09-12 | — | — | US | disclosed |
| US-4092318-A | HYPOTENSIVES | E. R. SQUIBB & SONS, INC. (US) | 1978-05-30 | — | — | US | disclosed |
| US-4053596-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1977-10-11 | — | — | US | disclosed |
| US-4044040-A | HYPERTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1977-08-23 | — | — | US | disclosed |
| US-3984419-A | HYPOTENSIVES | E. R. SQUIBB & SONS, INC. (US) | 1976-10-05 | — | — | US | disclosed |