Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 20/20 | 1.00 |
| ▸ | CHRM2 | P08172 | 16/20 | 1.00 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.83 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4979191 | 1.00 | CCR5 (1.00) | CCR5CHRM2CHRM1CHRM3 | |
| SCHEMBL4979182 | 1.00 | CCR5 (1.00) | CCR5CHRM2CHRM1CHRM3 | |
| SCHEMBL4453513 | 1.00 | CCR5 (1.00) | CCR5CHRM2CHRM1CHRM3 | |
| SCHEMBL5076337 | 0.91 | CCR5 (1.00) | CCR5CHRM2CHRM1CHRM3 | |
| SCHEMBL5076339 | 0.91 | CCR5 (1.00) | CCR5CHRM2CHRM1CHRM3 | |
| SCHEMBL14529305 | 0.91 | CCR5 (1.00) | CCR5CHRM2CHRM1CHRM3 | |
| SCHEMBL12796167 | 0.91 | CCR5 (0.83) | CCR5CHRM2CHRM1CHRM3 | |
| SCHEMBL13484306 | 0.88 | CCR5 (0.84) | CCR5CHRM2CHRM1CHRM3 | |
| SCHEMBL10073315 | 0.87 | CCR5 (1.00) | CCR5CHRM2CHRM1CHRM3 | |
| SCHEMBL10083413 | 0.87 | CCR5 (0.83) | CCR5CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114729023-A | anti-CCR5 agents and methods of treatment that block cancer metastasis or enhance cell death induced by DNA damage chemotherapy | 西托戴恩股份有限公司 | 2022-07-08 | — | — | CN | disclosed |