Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23043368 | 0.80 | NR4A2 (0.40) | KRAS | |
| SCHEMBL29680567 | 0.80 | NR4A2 (0.40) | KRAS | |
| SCHEMBL29921963 | 0.76 | NPC1 (0.37) | KRAS | |
| SCHEMBL23043008 | 0.76 | NPC1 (0.37) | KRAS | |
| SCHEMBL29418898 | 0.69 | NPC1 (0.47) | KRAS | |
| SCHEMBL23043082 | 0.69 | NPC1 (0.47) | KRAS | |
| SCHEMBL25310033 | 0.69 | SOS1 (0.36) | — | |
| SCHEMBL26965094 | 0.69 | HAVCR2 (0.49) | KRAS | |
| SCHEMBL23950893 | 0.68 | NR4A2 (0.44) | — | |
| SCHEMBL30240629 | 0.68 | NR4A2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114615981-A | KRAS G12D inhibitors | 米拉蒂治疗股份有限公司 | 2022-06-10 | — | — | CN | disclosed |