Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL965767 | 0.88 | PPARG (0.38) | FFAR4CDC7IRAK4 | |
| SCHEMBL965770 | 0.88 | PPARG (0.38) | FFAR4CDC7IRAK4 | |
| SCHEMBL27772698 | 0.88 | NPY5R (0.38) | CDC7IRAK4 | |
| SCHEMBL962196 | 0.87 | CXCR2 (0.36) | FFAR4USP2ALDH1A1POLBMAPT | |
| SCHEMBL962198 | 0.87 | CXCR2 (0.36) | FFAR4USP2ALDH1A1POLBMAPT | |
| SCHEMBL28781981 | 0.84 | HDAC3 (0.35) | MAPT | |
| SCHEMBL28782016 | 0.83 | IRAK4 (0.31) | FFAR4IRAK4 | |
| SCHEMBL5127599 | 0.83 | CDC7 (0.35) | FFAR4CDC7IRAK4 | |
| SCHEMBL5127585 | 0.83 | CDC7 (0.35) | FFAR4CDC7IRAK4 | |
| SCHEMBL27772660 | 0.83 | PPARG (0.38) | CDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101646653-A | Fused ring compounds as partial agonists of ppar-gamma | TAKEDA PHARMACEUTICAL JP | 2010-02-10 | — | — | CN | disclosed |