Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 16/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.51 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.50 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | KIT | P10721 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2877898 | 0.91 | EPHX2 (0.68) | P2RY1EPHX2STING1P2RY14CA12 | |
| SCHEMBL2877421 | 0.90 | NPC1 (0.60) | P2RY1EPHX2STING1CA12CA1 | |
| SCHEMBL2878683 | 0.89 | P2RY1 (0.52) | P2RY1EPHX2STING1 | |
| SCHEMBL2878559 | 0.88 | MAPT (0.59) | P2RY1EPHX2STING1CA12CA1 | |
| SCHEMBL14640383 | 0.87 | EPHX2 (0.59) | P2RY1EPHX2STING1P2RY2P2RY14 | |
| SCHEMBL2872551 | 0.87 | EPHX2 (0.62) | P2RY1EPHX2STING1CA12CA1 | |
| SCHEMBL2875049 | 0.85 | P2RY1 (0.57) | P2RY1EPHX2STING1P2RY2P2RY14 | |
| SCHEMBL2875822 | 0.85 | P2RY1 (0.60) | P2RY1EPHX2STING1P2RY14CA12 | |
| SCHEMBL2875876 | 0.85 | EPHX2 (0.62) | P2RY1EPHX2STING1P2RY2P2RY14 | |
| SCHEMBL2877993 | 0.85 | EPHX2 (0.59) | P2RY1EPHX2STING1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899299-B1 | C-LINKED CYCLIC ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS | BRISTOL MYERS SQUIBB CO (US) | 2010-10-20 | — | — | EP | claimed |