Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 16/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2878243 | 0.89 | P2RY1 (0.56) | P2RY1EPHX2STING1 | |
| SCHEMBL2878250 | 0.89 | EPHX2 (0.56) | P2RY1EPHX2CHRM3STING1 | |
| SCHEMBL2878651 | 0.87 | MAPT (0.58) | P2RY1EPHX2STING1 | |
| SCHEMBL2877898 | 0.87 | EPHX2 (0.68) | P2RY1EPHX2STING1 | |
| SCHEMBL14640383 | 0.86 | EPHX2 (0.59) | P2RY1EPHX2STING1 | |
| SCHEMBL2877421 | 0.84 | NPC1 (0.60) | P2RY1EPHX2STING1 | |
| SCHEMBL2872551 | 0.84 | EPHX2 (0.62) | P2RY1EPHX2STING1 | |
| SCHEMBL2872757 | 0.83 | P2RY1 (0.54) | P2RY1EPHX2CHRM3STING1 | |
| SCHEMBL2873323 | 0.82 | P2RY1 (0.53) | P2RY1EPHX2CHRM3STING1 | |
| SCHEMBL2875822 | 0.82 | P2RY1 (0.60) | P2RY1EPHX2STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899299-B1 | C-LINKED CYCLIC ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS | BRISTOL MYERS SQUIBB CO (US) | 2010-10-20 | — | — | EP | claimed |