SCHEMBL28783263

SCHEMBL28783263

CC(C)(CC(O)(CN1CC=Cc2cnccc21)C(F)(F)F)c1cc(N2CCCCC2)cc2c1OCC2

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 20/20 0.44
NR3C2 P08235 19/20 0.44
PGR P06401 15/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL292331 0.78 NR3C1 (0.58) NR3C1NR3C2PGR
SCHEMBL27754126 0.76 NR3C1 (0.57) NR3C1NR3C2PGR
SCHEMBL4436927 0.75 NR3C1 (0.41) NR3C1NR3C2PGR
SCHEMBL27754118 0.72 NR3C1 (0.46) NR3C1NR3C2PGR
SCHEMBL27769831 0.72 NR3C1 (0.46) NR3C1NR3C2PGR
SCHEMBL4477721 0.65 NR3C1 (0.68) NR3C1NR3C2PGR
SCHEMBL4485522 0.65 NR3C1 (0.66) NR3C1NR3C2PGR
SCHEMBL4484510 0.64 NR3C1 (0.58) NR3C1NR3C2PGR
SCHEMBL292162 0.63 NR3C1 (0.56) NR3C1NR3C2PGR
SCHEMBL6384902 0.63 NR3C1 (0.47) NR3C1NR3C2PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101553214-A Compositions and methods for treating, controlling, reducing, ameliorating, or preventing allergy BAUSCH & LOMB (US) 2009-10-07 CN disclosed
CN-101528208-A Compositions and methods for treating or preventing glaucoma or its progression BAUSCH & LOMB (US) 2009-09-09 CN disclosed